Intrinsic factor-rationale: vitamin b12 absorption depends on intrinsic factor, which is secreted by parietal cells in the stomach. the vitamin binds with intrinsic factor and is absorbed in the ileum. hydrochloric acid, histamine, and liver enzymes dont influence vitamin b12 absorption.client needs category: physiological integrityclient needs subcategory: pharmacological and parenteral therapiescognitive level: knowledgereference: smeltzer, s.c., et al. brunner and suddarths textbook of medical surgical-nursing, 11th ed. philadelphia: lippincott williams & wilkins, 2008, p. 1123.