Vesicle-rationale: a vesicle is a circumscribed skin elevation filled with serous fluid. a flat, nonpalpable, colored spot is a macule. a solid, elevated, circumscribed lesion is a papule. an elevated, pus-filled, circumscribed lesion is a pustule.client needs category: physiological integrityclient needs subcategory: basic care and comfortcognitive level: comprehensionreference: weber, j., and kelley, j. health assessment in nursing, 3rd ed. philadelphia: lippincott williams & wilkins, 2007, p. 178.