What is the usual outcome of a pulmonary granuloma after treatment?

Scarring and calcification-pulmonary granulomas heal by scarring and calcification (dystrophic). Complete resolution is not possible because the lung tissue has been severely damage with destruction of underlying basement membrane. Therefore, regeneration and resolution is not possible.

Although tb can spread or disseminate, malignant neoplasms (cancers) usually metastasize or have the capacity to enter the blood supply or lymphatics and spread to distant organs or sites. Macrophages are involved in granulomatous inflammation but do not replace the granuloma. Granulomatous inflammation is a distinctive pattern of inflammation. Therefore, it cannot progress to chronic inflammation.