The least pressing on the hierarchy of needs put forth by Maslow is the self-actualization needs. This level is basically the level where passions and wants can easily be fulfilled. Since it is the last of the hierarchy levels, it is the least important. The idea is that following your passions, realizing your full potential, can be done after you have figured out the rest of the issues the hierarchy covers.
For those not in the know, the hierarchy, from lowest to highest, is as follows: physiological, safety, love/belonging, esteem, and self-actualization. At the lowest is the most basic of human needs, such as food, sleep, shelter, etc. Safety would be where abuse situations would fall. Love and belonging is making sure you have a family. Esteem is making sure you love yourself.