False-for many medicines, the time of day you take a medicine really does matter as it effects how high the levels of medication in your blood rise, and low they drop. in general, it is best to evenly space out the time you take a medicine (for example every 12 hours for a twice daily medicine), but with other medicines taking it with a regular meal is more important. also, your bodys chemistry changes a lot during the day which can make some medicines work better at different times, so always ask exactly when during the day each of your medicines should be taken.