The metabolic rate of cells in the body would be reduced-a reduction in the antidiuretic hormone would allow more water to be lost through the kidneys.thyroid stimulating hormone (tsh) affects the hormones in the thyroid gland. so a reduction in this hormone would cause a reduction in t4 and t5 which affect the regulation of celular metabolism. it also would reduce calcitonin which is used to lower blood calcium levels; without calcitonin calcium levels would stay high.blood calcium levels are lowered through the hormone calcitonin.somatostatin in the pancreas inhibits the release of glucagon, insulin, growth hormone, and digestive secretions.