There are a number of kinds of hemoglobin. Over the years, the hemoglobin changes through its many types. There is hemoglobin A, A2 and F. The hemoglobin F refers to fetal hemoglobin. Although most of this hemoglobin is replaced by A and A2, some hemoglobin F remains in the body. It can again be generated in times of need, especially when there is a defect in the hemoglobin A and A2.
All of these different hemoglobins are present in the blood and are made by the stem cells. The hemoglobin consist of four protein chains. The different configurations of these chains determines the type of hemoglobin that is produced.