Les 100 simply means "The 100". The word "les" is a French word, which means "the." Hence, the meaning of "Les 100" is "The 100". Les 100, which is pronounced as "The hundred," is actually an American TV series, a post-apocalyptic sci-fi drama.
This drama was premiered on The CW on 19th March 2014 and lasts till 30th September 2020. This series was developed by Jason Rothenberg and is based on a novel series titled "Les 100", written by Kass Morgan.
This series was made after a group of post-apocalyptic survivors, which contains some criminal adolescents that include Finn Collins, Octavia Blake, Monty Green, John Murphy, Wells Jaha, Jasper Jordan, Raven Reyes, Bellamy Blake, and Clarke Griffin. These people are among the first from "the Ark," a space habitat, that return to the earth following a devastating nuclear apocalypse. There are some other lead characters like Dr. Abbiy Griffin, Marcus Kane, and more.