Perimenopause is the period around the cessation of monthly menstrual bleeding. It is the time from the fertile reproduction period to postmenopausal. This time can last anywhere from 4 years up to eight years. The end of perimenopause is one year after your last period and the level of estrogen declines during perimenopause.
The hormonal imbalance is the outcome of perimenopause symptoms—patients present with irregular menstruation, heavy bleeding, and scattered bleeding during premenopause. There are also hot flashes and reduced sexual drive. Menopause is the interruption of primary ovarian functions. This event typically occurs around the 40s and early 50s.
Estrogen and progesterone encourage the growth of the endometrial lining. When conception does not occur, the inner lining of the uterus sheds. In menopause, the readiness of follicles to mature under hormonal regulation of the pituitary lessens.
Serum levels of estrogen and progesterone drop, as does pituitary secretion. FSH and LH levels rise. Some of the characteristics of lack of estrogen include the dry vagina, reduced libido, hot flashes, watery vaginal discharge, urinary symptoms, joint pain, back pain, and depression.