Both of these medications are prescribed to treat diabetes type 2. The main difference between the two drugs is absorption, dosage, and half-life. Glipizide slows the intake of food when taken at five milligrams per day. Glyburide’s dosage is two and a half to five milligrams per day. Glipizide is more effective than most other drugs of this nature.
However, diabetes cannot be treated with this type of medication because the body cannot produce insulin. On the other hand, the trouble with type 2 diabetes is that what the body produces is improperly used. The side effects of these medications are dependent on the blood sugar levels of the patient.