What is the difference between Amine and Amide?

Amines can be considered as organic derivates of ammonia. Amines have nitrogen bonded to carbon. Amines can be grouped as primary, secondary, and tertiary amines. This classification is built on the number of organic groups that are connected to the nitrogen atom. Primary amino has one R group attached to the nitrogen; secondary amines are named alkylamines.

Amines have a trigonal bipyramidal shape around the nitrogen atom. Amines can also form ammonium salts where the nitrogen is attached to four groups, and they become positively charged. Amide is a derivative of carbonyl carbon with an attached R group. Amides with no substituents on the nitrogen can develop hydrogen bonds with each other. Melting and boiling points of such amides are elevated. In amines, nitrogen is directly one alk/aryl group.

When naming amides, the amide is used after the parent name. Amides are less basic than amines. Amides are resonance stabilized, and due to the inductive effect and they become less basic. Amine is an organic compound made up of one or more nitrogen atoms that are bonded to alkyl groups. Amide is an organic combination or molecules that contain nitrogen atoms linked to the carbon atom of the carbonyl group.

Amine and amide are two terms you would have most likely heard in chemistry if you ever offered or heard about the subject. Foremost, the amide is certainly an organic compound that has its group bonded as R-C=O, and it is connected to a nitrogen atom (N). Also, when you remove a positive ion of hydrogen from ammonia (NH3), you will obtain amide. This removal process can be referred to as deprotonation; and the result would be NH2, which is bonded to an acyl group. Also, when the hydroxyl group of a carboxylic acid is replaced with ammonia, the result would be amide. On the other hand, amines are also organic compounds that can be obtained from ammonia, but they are bonded with either aryl or an alkyl group. However, these aryl and alkyl bonds are also remnant of ammonia, after the removal of a hydrogen ion. Examples of amines include aniline and amino acids.

When it comes to the basicity of the two, you will notice that amine will have a weaker base as compared to the amide. The conjugate acid of amine will be 9.5, but the conjugate acid of amide will be at −0.5. If you would check their acid−base properties in the water, you will notice that the amides will not be too visible.

The formula of these two groups will also be different from each other. Amides will have a general structure, which means that the nitrogen atom will be connected to a carbonyl carbon atom. Take note that amines will have the tendency to become poisonous when they are stronger.

Discussing amide, it is a term in chemistry which refers to an organic compound. The group of the amide is had an R-C=O bond, which is connected to a nitrogen atom (N). An amide can also be derived when (NH3), which is ammonia, is deprotonated. When you deprotonate ammonia (NH3), an ion of hydrogen would be removed, thus resulting in NH2 being bonded with the R-C=O bond to an acyl group. When you substitute the hydroxyl of some acids, like carboxylic, with ammonia, amides are derived.

On the other hand, amines are also organic compounds, and they can be gotten from ammonia, but aryl or alkyl groups are the bonds between them. In order to name amides, you will add "amide" as a suffix behind the parent term. You can name amines by either adding the suffix "amine” or adding "amino" as prefix after and before the parent term, respectively.