Peripheral Vascular Disease is a broad term which is used to describe the diseases of the blood vessels outside the brain and heart. PVD mainly includes the arteries, both large and small, veins, capillaries and venules, which distributes the blood to and from all extremities, kidneys, and intestines. PVD has become a common condition which can lead to the loss of limbs or even death.
PVD is caused by diminished tissue perfusion occurring as a result of atherosclerosis accompanied by thrombi or emboli. In PAD, (Peripheral Artery disease) development of atherosclerotic plaques occurs in the walls of arteries mainly in limbs, intestines, and kidneys. PAD results in reduced tissue perfusion, and if it is not treated in time, it may lead to a certain kind of infection which causes gangrene, which can lead to amputation.