Latin is a term that relates to Latin America, language spoken in ancient Rome or other cities of Latium. It also relates to the script of the language spoken in ancient Rome. Spanish, on the other hand, is a term pertaining to Spain, her culture, people, and the Spanish language. In other words, it means a native of Spain or the language spoken in Spain.
The first difference between Latin and Spanish is that while Latin originated from Latium in Italy, Spanish originated from Spain. According to research, Latin is regarded as an ancient language, and it is no longer used as a native language, whereas the Spanish language was created from Latin scripts, and it is still being spoken till today by millions of people around the world. Since the Latin language is no longer being used as a native language, it can be regarded as a dead language, while Spanish is a living language.