Myeloma is a tumor of the plasma cells present in the blood, and there is no difference between the two terms myeloma and multiple myeloma. They are both representations of the same illness with updated terminology. Myeloma or multiple myeloma is a cancer of the plasma cells produced in the bone marrow.
Because of the overpopulation, this leads to the reduction of other cells produced in the bone marrow leading to anemia, reduced immunity, uncontrolled bleeding, repeated infections, the tendency toward bone pains and fractures, bone erosion, weight loss or loss of appetite.