“That” and “Who” are English words that are used in sentences. That and who are pronouns. Pronouns are words used instead of a noun.
That and who are used to express a person or a thing. That and who are relative pronouns. Relative pronouns act as a substitute for a noun and also acts as a word use to join two clauses together.
They are used together most times.
For example, who gave that boy my pen?
However, their major difference is that “WHO” is used is used to relate to a person only for example, who locked the door while “THAT” is use to relate to a person or an object.
For example, that car is faulty (an object) and that man is my father (a person).