There is no big difference between Roxicodone and oxycodone. They are narcotic drugs for a pain reliever. The basic difference between oxycodone and Roxicodone is that, oxycodone is the most common name for the drug, while Roxicodone is just a brand name of the same drug. This means, when you are talking about oxycodone, you are as well referring to Roxicodone. Roxicodone has the same composition as oxycodone.
Oxycodone is used for suppressing pains. And it is also used by those who are coughing because it helps to reduce the pains experienced while coughing. Oxycodone does not stop the sensation of pain but rather reduce its effect. Oxycodone is used to people manage their pains. Oxycodone, however, has some side effects and that's why it is always advised to use the drug with caution. However, oxycodone can cause depression, headache, nausea, it can also depress breathing in old people and this can lead to abnormal heartbeats.