Protons, along with neutrons, are made of tiny particles called quarks, permanently combined after the universe cooled for a few moments from the big bang. Atoms are made of protons, neutrons and electrons. All three of them were once thought of being fundamental particles, which cannot be broken up into anything smaller.
It was discovered, after the invention of the particle accelerator, that electrons are fundamental particles, but neutrons and protons are not. Neutrons and protons are made up of quarks, which are held together by Gluons.
There are six types of quarks called flavours. The flavours are up, down, strange, charm, top, and bottom. Up, charm and top quarks have a charge of +2⁄3, while down, strange and bottom quarks have a charge of -1⁄3. Each quark has a matching antiquark. Antiquarks have a charge opposite to that of their quarks. Hence, up, charm and top antiquarks have a charge of -2⁄3 and that down, strange and bottom antiquarks have a charge of +1⁄3.