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Is it apparent that there are spare receptors comparing the two graphs?

Is it apparent that there are spare receptors comparing the two graphs? <br/><img src="http://accesspharmacy.mhmedical.com/data/books/trev10/m_trev10_c002f001.png"/>

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Graphs B and C show Physiological effect vs concentration and Binding vs concentration for the same drug respectively.

Asked by Uncadf, Last updated: Nov 09, 2024

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uncadf

uncadf

uncadf
Uncadf

Answered Oct 31, 2018

No

Spare receptors occur when Emax occurs at less than 100% binding. In other words, when EC50 is less than Kd, spare receptors are present. The two are equal in this figure.
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