Which of the following is the main effect of bile acid sequestrants?

Decrease LDL

(A) is the correct answer. BEcause the liver must compensate for the loss of cholesterol, it will increase the number of LDL receptors to take up more LDL particles. (B) is technically true as well, but the decrease in LDL is honestly the most clinically important. (C) is actually false, but the decrease in LDL is much more relevant. (D) is a trick answer as lowering HDL is not desirable when treating dyslipidemia. While some answers are technically true, the clinical importance of LDL, as seen by guidelines from 2004, is evident. LDL reduction is an important part of treatment of dyslipidemia.