Which class of drugs is most likely to suppress his chemotherapy-related nausea? A 22-year-old white man with metastatic testicular carcinoma is undergoing treatment with high doses of cisplatin.
One of the main reasons people hate chemotherapy is due to the definite nausea they will suffer. Having to endure chemotherapy from having cancer is terrible enough, but the nausea is just as bad. If a twenty-two year old man has metastic testicular carcinoma, he will undergo treatments of chemotherapy with high doses of cisplatin.
Today, there are certain drugs that can be administered to the patients prior to their chemotherapy treatments that will cause the patient to not suffer from the nausea.
However, not all of the chemotherapy treatments have nausea treatments, but only certain treatments. One drug that will suppress the nausea is serotonin 5-HT3 antagonists. Taking this drug may have some side effects like most drugs do, but it will stop the nausea.
The correct answer is A. The most effective drugs for the treatment of chemotherapy induced nausea are the serotonin 5-HT3 antagonists. This class includes ondansetron, dolasetron, and granisetron. These drugs can cause fatigue, headache, constipation, urinary retention, and dizziness; however, setrons are generally not very toxic
Answer B is incorrect. Benzodiazepines include lorazepam and diazepam. They may be effective in treatment of the anticipatory nausea associated with chemotherapy, but they are not as effective as the 5-HT3 antagonists
Answer C is incorrect. Cholinergic antagonists include scopolamine. These drugs are not used for the treatment of chemotherapy-induced nausea. They are used for motion sickness
Answer D is incorrect. Histamine receptor antagonists include diphenhydramine and promethazine. They are used for acid reflux and allergies.
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